ORANVATE SKIN LIGHTENING & BRIGHTENING GEL 30g Oranvate gel is used in short courses to treat severe inflammatory skin disorders, such as those below, when milder corticosteroids have not been effective.Acting as anti inflammatory, anti allergic and antipruritic. It is particularly indicated in treatments of the most resistant dermatoses.Skin disorder called discoid lupus erythematosus, which is caused by the immune system attacking the skin.Oranvate gel contain the active ingredient clobetasol propionate, which is a type of medicine called a topical corticosteroid.Corticosteroids (also known as steroids) are medicines used for reducing inflammation. Skin inflammation may occur as a result of an allergic reaction, or irritation of the skin. It is caused by the immune system releasing substances that make blood vessels in the skin widen. This makes the irritated area become red, swollen, itchy and painful, as is seen in dermatitis or eczema.When clobetasol is applied to the skin it works by acting inside the skin cells to decrease the release of these inflammatory substances. This reduces swelling, redness and itch.There is a range of potencies of corticosteroids applied to the skin. Clobetasol propionate is classed as a very potent corticosteroid. It is prescribed to treat severe inflammatory skin disorders such as eczema and psoriasis that have not responded to weaker corticosteroids.Oranvate gel is more greasy than the cream. It is more suitable for very dry, scaly areas of skin, whereas moist or weepy skin is best treated with the cream.